Enhanced tissue regeneration through immunomodulation of angiogenesis and osteogenesis with a multifaceted nanohybrid modified bioactive scaffold.

The level of iNOS showed a trend of gradual decline, while the level of IL-6 was relatively stable and declined from 6 h onwards ( Fig. 3 I–J). 2.4 Determination of the osteogenic ability of the nanohybrids and the immune crosstalk between osteogenesis and angiogenesis The osteogenic ability of tissue engineered materials is very important for the repair and regeneration of bone defects.

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