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Orthopedic Surgery Causes Gut Microbiome Dysbiosis and Intestinal Barrier Dysfunction in Prodromal Alzheimer Disease Patients: A Prospective Observational Cohort Study.

Ann Surg · 2022 · PMC9259038 · PMID 35766370

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Preoperative baseline levels of plasma occludin and claudin-1 were elevated in the pAD groups than those in the NC group, but the differences did not reach statistical significance (Supplementary Fig. 6, Supplemental Digital Content 1, http://links.lww.com/SLA/D918 ).

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