Neocortical neurons cultured from these Khsrp fl/fl × Syn1:Cre mice also showed increased axon and dendrite lengths and branching consistent with the alterations seen in neurons from the Khsrp −/− mice, but notably dendrite lengths did not reach statistical significance (Fig. 4g, h ).
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KHSRP loss increases neuronal growth and synaptic transmission and alters memory consolidation through RNA stabilization.
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