In our experimental data, after DMNQ treatment, on the one hand, the cells showed a trend of shrinking, rounding, and falling off morphologically; on the other hand, the qPCR results showed that FOXO1 , FOXO3 , MuRF1 , and Atrogin1 were significantly upregulated, and the Western blot results showed that the protein expression of MuRF1 and Atrogin1 was increased, and the protein expression of MyHC was decreased.
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Construction and Analysis of Disuse Atrophy Model of the Gastrocnemius Muscle in Chicken.
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