When applied to skin wound healing fibroblast-as well as MSC-derived ECM showed a trend towards better wound healing, although no significant differences in wound closure or revascularization were evident as compared to delivery vehicles lacking the respective cell-derived matrices [ 84 , 88 ].
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Engineering microparticles based on solidified stem cell secretome with an augmented pro-angiogenic factor portfolio for therapeutic angiogenesis.
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