The role of inflammation and the possibilities of inflammation reduction to prevent cardiovascular events.

1 conducted a large meta-analysis finding moderate, but highly significant, associations between markers of systemic inflammation and its intensity [namely fibrinogen, C-reactive protein (CRP), albumin, and leucocytes’ count] and coronary heart disease (CHD).

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54 However, of importance is that the treatment arms of 50 and 300 mg canakinumab did not reach statistical significance as compared with placebo.

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