Barely Significant
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Evaluation of a Multivalent Transcriptomic Metric for Diagnosing Surgical Sepsis and Estimating Mortality Among Critically Ill Patients.

JAMA Netw Open · 2022 · PMC9277492 · PMID 35819783

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Among patients with suspected sepsis at the time of enrollment (cohort A plus the crossover cohort on day of suspected sepsis), IMX-BVN-3 had a greater AUROC (0.80 [95% CI, 0.62-0.97]) than either procalcitonin (AUROC, 0.64 [95% CI, 0.37-0.91]; P = .38) or IL-6 (AUROC, 0.58 [95% CI, 0.37-0.80]; P = .08) levels for the detection of bacterial infection but did not reach statistical significance (eFigure 1B in the Supplement ).

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