A post-hoc analysis of a randomized control trial showed a trend towards improved outcomes with lower target glucose control compared with conventional control in patients with A1C < 5.0%, even though hypoglycemia was more prevalent (adjusted hazard ratio 0.60, 95% CI 0.35–1.01; P = 0.052).
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Association between time in range of relative normoglycemia and in-hospital mortality in critically ill patients: a single-center retrospective study.
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The sentences
On the other hand, the association between a TIR of absolute normoglycemia > 80% and mortality was almost significantly dependent on A1C levels.