International cohort study on the effectiveness of dronedarone and other antiarrhythmic drugs for atrial fibrillation in real-world practice (EFFECT-AF).

Europace · 2022 · PMC9282916 · PMID 34792111

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marginally non-significantno p-value reported

22 The difference found in the mortality rates, statistically significant in the on-treatment analysis and marginally non-significant in the intention-to-treat analysis, is aligned with results from ATHENA and AFFIRM trials.

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showed a trendno p-value reported

Similar to that found in pivotal studies, people on dronedarone showed a trend towards less cardiovascular hospitalizations and mortality in real-world practice although this was reported only in the on-treatment analysis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.