Multiplex analysis of mass imaging data: Application to the pathology of experimental myocardial infarction.

When both the intensity of each individual immunoreactive centre and the total area of these centres were taken into account through application of the InDen measurement, strong ( R 2 > 0.85) and highly significant ( P < .01) correlations were determined between MPO and HO‐1 expression as well as between MPO and pP38 expression (Figure 4C,D ).

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However, the correlation between areas alone, ie, corresponding comparison of the percentage area, did not reach statistical significance although this remained a moderate trend (Figure 4E,F ).

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