Impact of Policy Interventions on Oxycodone Prescribing in Queensland, Australia: An Uncontrolled Interrupted Time Series Study.

Compared with the model that included all hospitals, the sensitivity analysis demonstrated a lower baseline proportion ( β 0 ) (48.5%, 95% CI 47.2–49.8; p < 0.001), a higher baseline trend ( β 1 ) (0.5%, 95% CI 0.4–0.5; p < 0.001), a higher level of change post-QMHAC restrictions ( β 2 ) (11%, 95% CI 9.1–12.8; p < 0.001), a negative trend after QHMAC restcitions ( β 3 ) (− 0.2%, 95% CI − 0.3 to − 0.1; p < 0.001), a reduced level of change post-PBS restrictions ( β 4 ) (3.7%, 95% CI 1.8–5.5; p < 0.001), and a similar trend after PBS restrictions ( β 5 ) (− 0.2%, 95% CI − 0.3 to − 0.1; p < 0.001).

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