Our plots on systemic circulation lifetime in mouse versus nanoparticle elasticity reveal a non-monotonic relationship, rather than a monotonic one as claimed by prior reports (Supplementary Table 1 ), though plots of normalized cellular uptake versus nanoparticle elasticity lack a clear trend as did in prior reports (Supplementary Table 2 ).
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Nanoparticle elasticity affects systemic circulation lifetime by modulating adsorption of apolipoprotein A-I in corona formation.
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