Also, AA supplementation caused a nonsignificant trend toward suppression of serum TNF-α levels (the other inflammatory cytokine) elevated in HFD-fed GLUT10 G128E mice (Fig. 4 E).
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Vitamin C attenuates predisposition to high-fat diet-induced metabolic dysregulation in GLUT10-deficient mouse model.
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The AA group had a trend toward reduced body fat composition in HFD-fed WT mice, but the difference did not reach statistical significance (Fig. 3 A and B).