Alterations of NK Cell Phenotype During Pregnancy in Multiple Sclerosis.

Interestingly, cluster 7 with a mixed composition of CD56 bright and CD56 dim NK cells displayed high levels of NKp46, NKG2D and NKG2A comparable to the CD56 bright clusters 4 and 11 indicating that a minor fraction of CD56 dim NK cells shares the same expression pattern predominantly found on CD56 bright NK cells (see cluster 7, frequency changes of cluster 3 with a comparable marker expression did not reach statistical significance, Figures 3B, C ).

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