Loss of response to anti-TNFα agents depends on treatment duration in patients with inflammatory bowel disease.

Aliment Pharmacol Ther · 2021 · PMC9292495 · PMID 34559428

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

did not reach statistical significanceP = 0.09so close (0.05 < p ≤ 0.1)

However, in patients with UC, the decrease in anti‐TNFα discontinuation for side effects and the increase of anti‐TNFα discontinuation for remission did not reach statistical significance ( P = 0.09 and P = 0.07 respectively).

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