Irisin treatment lowers levels of phosphorylated tau in the hippocampus of pre-symptomatic female but not male htau mice.

Neuropathol Appl Neurobiol · 2021 · PMC9292848 · PMID 33768561

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showed a trendno p-value reported

While not statistically significant, TNFα levels in female htau brainstem and prefrontal cortex showed a trend towards similar irisin‐related reductions (Figure 3B ).

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