Previous and recent multicenter, randomized controlled trials showed a trend towards reduced mortality in favor of V‐V ECMO over conventional treatment. 6 , 7 Furthermore, in a recently published meta‐analysis of these trials, 60‐day mortality was significantly lower in the V‐V ECMO group. 8 Although mortality rates in V‐V ECMO are lower compared with other ECMO modalities, a substantial quote of patients still die during hospital admittance. 9 According to the Extracorporeal Life Support Organization (ELSO), more than 75 000 ECMO runs for respiratory compromise have been performed in more than 450 centers (as of July 2021).
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Defining and understanding the "extra-corporeal membrane oxygenation gap" in the veno-venous configuration: Timing and causes of death.
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