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LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson's disease.

NPJ Parkinsons Dis · 2022 · PMC9296523 · PMID 35853899

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a clear trendno p-value reported
3h , there is a clear trend toward an increase in GCase activity in LRRK2 G2019S fibroblasts compared to controls, confirming the results of the in-lysate assay.

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