Activation function 1 of progesterone receptor is required for mammary development and regulation of RANKL during pregnancy.

Sci Rep · 2022 · PMC9296660 · PMID 35854046

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0900

boldest claim

The sentences

showed a trendp > 0.05actually significant

However, AF1_FFF mutations had no significant effect on the expression of Pgr or Esr1 although Pgr expression on GD7.5 showed a trend of upregulation (p > 0.05).

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marginally significantp = 0.06so close (0.05 < p ≤ 0.1)

Third, the levels of PGR proteins appear lower in the mutant on GD3 but higher on GD7.5 in the mutant, although the changes are marginally significant for PGRA (Fig. 5 b, p = 0.06).

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marginal significancep = 0.09so close (0.05 < p ≤ 0.1)

The 22 kDa RANKL was reduced on GD3 with marginal significance (Fig. 5 b, p = 0.09).

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