Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Autistic-Like Behaviors of SHANK3 Mutant Beagle Dogs.

And in the 3-month visit, an increasing trend in the duration of sniffing and licking was also observed in the SHED-treated mutant dogs, but this did not reach statistical significance ( Fig. 2E ).

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Compared with pre-treatment, SHED-treated mutant beagle dogs showed a decreasing trend of IFN-γ in 1-month post-treatment and an increasing trend of IL-10 in 3-month post-treatment ( Fig. 3C ).

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