Rare genetic variants in genes and loci linked to dominant monogenic developmental disorders cause milder related phenotypes in the general population.

Nonetheless, a Bonferroni-corrected significant result was seen across all gene subsets for shorter stature, reduced chance of having a degree, and increased TDI; lower fluid intelligence, lower income, higher BMI, and an increased chance of being diagnosed with a child DD also remained nominally significant even in the 25 gene subset.

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