The metabolic hormone adiponectin affects the correlation between nutritional status and pneumococcal vaccine response in vulnerable indigenous children.

Further, we observed a borderline significant association between ghrelin levels and post-vaccination antibody levels in overweight children (regression coefficient 0.009, p = 0.02) ( Table 3 ).

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In line with our previous results, multivariable analysis showed a trend towards higher antibody levels in stunted compared with non-stunted children (regression coefficient 0.92, 95% CI -0.015–1.85, Table 3 ).

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