Off-target inhibition of NGLY1 by the polycaspase inhibitor Z-VAD-fmk induces cellular autophagy.

FEBS J · 2022 · PMC9304259 · PMID 34995415

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showed a trendno p-value reported

It is notable that similar experiments with K562 NGLY1 KD cells mirror these observations and also showed a trend towards increased protein aggregation, rather than a significant difference [ 25 ].

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