Engineered biomimetic nanoparticles achieve targeted delivery and efficient metabolism-based synergistic therapy against glioblastoma.

We detected a clear trend: the Ki67, LDHA, and MCT4 levels were increased from grade II to grade III and gained to grade IV (Fig. 2b ), and there was a positive correlation between the levels of above LA metabolic indicators and the extent of glioma proliferation (Supplementary Fig. 1 ).

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