Feeding desensitizes A1 adenosine receptors in adipose through FOXO1-mediated transcriptional regulation.

Mol Metab · 2022 · PMC9304768 · PMID 35811051

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did not reach statistical significanceno p-value reported

We then compared A1R mRNA expression in isolated adipocytes from overnight fasted mice and confirmed that HFD also results in significantly reduced expression of A1R mRNA in mice within gWAT and trended towards decreased in BAT but did not reach statistical significance.

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