PET as a Translational Tool in Drug Development for Neuroscience Compounds.

Clin Pharmacol Ther · 2022 · PMC9305164 · PMID 35201613

Europe PMC DOI

hedged sentence

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

did not reach statistical significanceP = 0.054so close (0.05 < p ≤ 0.1)

The difference did not reach statistical significance ( P = 0.054), but the greatest accuracy in predicting a 25% and 50% of reduction in PANSS or BPRS corresponded to occupancy measures of 60% and 78%, respectively, confirming that this is the range of occupancy associated with a clinical effect.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.