Polygenic risk scores for neuropsychiatric, inflammatory, and cardio-metabolic traits highlight possible genetic overlap with suicide attempt and treatment-emergent suicidal ideation.

The largest effect was found in CATIE, albeit with a large standard error, while the most significant effect was found in STAR*D, where all the tested P T showed nominally significant associations ( p = .03–2.5 × 10 −3 , R 2 = 0.5%–1.1%; Table S4 ).

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