Acute response to cholinergic challenge predicts long-term response to galantamine treatment in patients with Alzheimer's disease.

Acute improvements in saccadic eye movements that were observed after single dose galantamine did not clearly predict long‐term clinical improvement: saccadic peak velocity increased on average in responders but not in non‐responders, but this failed to reach statistical significance (Table 2 ).

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In addition, a highly significant effect on the nausea VAS score was found, which may have particularly had an impact on tests that required sustained attention or active participation.

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