Among those with positive PD‐L1 expression (TC1/2/3 or IC1/2/3) treated with atezolizumab, an elevated pretreatment LDH level was associated with a nonsignificant trend of worse PFS and OS; this likely reflected the small patient numbers.
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Pre- and on-treatment lactate dehydrogenase as a prognostic and predictive biomarker in advanced non-small cell lung cancer.
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Among those with TC1/2 or IC1/2, elevated pretreatment LDH was similarly associated with worse PFS but did not reach statistical significance (Fig. 6 ).