Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) R47H Variant Causes Distinct Age- and Sex-Dependent Musculoskeletal Alterations in Mice.

The TREM2 R47H/+ femurs also showed a trend toward decreased tissue mineral density (TMD) (Fig. 3 C ) of the cortical bone compared to WT littermates but have similar mechanical and estimated material properties of the femur at 20 months of age by three‐point bending compared to WT mice (Fig. 3 C ).

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