Overexpression of the miR-17-92 cluster in colorectal adenoma organoids causes a carcinoma-like gene expression signature.

Neoplasia · 2022 · PMC9307940 · PMID 35872559

Europe PMC DOI

hedged sentence

0.0620

closest p · 1.2× alpha

0.0620

boldest claim

The sentences

did not reach statistical significancep-value=0.062so close (0.05 < p ≤ 0.1)

However, this did not reach statistical significance (p-value=0.062). miR-17-92 overexpression has no effect on organoid proliferation Next, we investigated whether the overexpression of the miR-17-92 cluster induced cancer-specific characteristics in the adenoma organoids.

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