Primary cicatricial alopecias are characterized by dysregulation of shared gene expression pathways.

PNAS Nexus · 2022 · PMC9308563 · PMID 35899069

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highly significantno p-value reported

In PCAs, the immunopanel analysis revealed a striking and highly significant MC signature (represented by TPSAB1, MS4A2, and CMA1), in LPP, FFA, and CCCA lesions (Fig. 3A – C ) a Th1 signature (CD4, IFNg, STAT4, and IL12).

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did not reach statistical significanceno p-value reported

The fibrosis pathway in CCCA was also increased, but did not reach statistical significance (not shown).

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