Evidence of cerebellar TDP-43 loss of function in FTLD-TDP.

Compared to controls, a significant or nominally significant decrease in cerebellar TDP-43 was seen in FTLD-TDP cases in unadjusted analysis (β: − 0.4087, 95% CI: − 0.6325 to − 0.1849, P = 0.0004, Fig. 1 B, Table 2 ) and analysis adjusted for age and sex (β: − 0.2701, 95% CI: − 0.4850 to − 0.05514, P = 0.0142, Table 2 ), respectively.

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