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High-Density Lipoprotein Changes in Alzheimer's Disease Are <i>APOE</i> Genotype-Specific.

Biomedicines · 2022 · PMC9312991 · PMID 35884800

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APOE3E3 MCI and AD patients exhibited lower LCAT activity, and APOE3E3 MCI patients had significantly lower HDL CEC than the controls, while the HDL particles of APOE3E3 AD patients exhibited a wider variability, and thus, the decrease in HDL CEC did not reach statistical significance.

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