The Effect of SGLT2 Inhibitor Dapagliflozin on Serum Levels of Apelin in T2DM Patients with Heart Failure.

Biomedicines · 2022 · PMC9313111 · PMID 35885056

Europe PMC DOI

hedged sentences

0.2400

closest p · 4.8× alpha

0.2400

boldest claim

The sentences

showed a trendp = 0.24not close (p > 0.1)

The concentrations of NT-proBNP showed a trend to decrease from 988 (25–75% IQR = 745–1126) pmol/mL to 843 (25–75% IQR = 697–985) pmol/mL (Δ% = −14.7%, p = 0.24). 3.3.

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borderline significanceno p-value reported

Multivariate logistic regression showed that relative changes of LVEF, LA volume index, and early diastolic blood filling to longitudinal strain ratio were strongly associated with the levels of apelin, whereas NT-proBNP exhibited a borderline significance in this matter.

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