Collagen Turnover Biomarkers Associate with Active Psoriatic Arthritis and Decrease with Guselkumab Treatment in a Phase 3 Clinical Trial (DISCOVER-2).

Rheumatol Ther · 2022 · PMC9314487 · PMID 35352313

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did not reach statistical significanceno p-value reported

C10C and PRO-C1 also trended toward upregulation in PsA patients compared with healthy controls, but the difference did not reach statistical significance (1.17-fold; ESM Fig. 1).

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