Heritability Analyses Uncover Shared Genetic Effects of Lung Function and Change over Time.

Genes (Basel) · 2022 · PMC9316642 · PMID 35886044

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near-significantno p-value reported

In the interaction analysis, we observed that the annual change in post-bronchodilator FEV 1 /FVC, FEV 1 /FVC, and MVV showed a significant or near-significant SNP–smoking interaction, thus allowing us to infer the amount of genetic variance that would be affected by smoking.

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a decreasing trendno p-value reported

The average profile plots of the eight lung functions at each period showed a decreasing trend for all lung functions ( Figure 1 b,c).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.