Aryl Hydrocarbon Receptor (AhR)-Mediated Signaling in iPSC-Derived Human Motor Neurons.

Pharmaceuticals (Basel) · 2022 · PMC9321538 · PMID 35890127

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did not reach statistical significanceno p-value reported

In the presence of various concentrations of TCDD (0.25–10 nM), reduction in AhRR levels was consistently observed but was variable and did not reach statistical significance as compared to control.

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a possible trendno p-value reported

reported a significant increase in AhR following induction of neural differentiation, which was not observed in our motor neurons, where the levels of AhR expression were fairly similar in the two populations, with a possible trend toward reduction in neurons.

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