A highly significant difference was found in the CA1 field, where AD cases had many more strongly CASP-6-immunoreactive neurons than HC (illustrated in Figure 10 ).
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NLRP1 Inflammasome Activation in the Hippocampal Formation in Alzheimer's Disease: Correlation with Neuropathological Changes and Unbiasedly Estimated Neuronal Loss.
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Compared to HC, NLRP1 was also much more strongly expressed in the subiculum in AD cases of our series, but—probably due to the small sample size—did not reach statistical significance.