Frailty and checkpoint inhibitor toxicity in older patients with melanoma.

Cancer · 2022 · PMC9325486 · PMID 35439334

Europe PMC DOI

hedged sentence

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closest p · 1.2× alpha

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The sentences

showed a trendP = .06so close (0.05 < p ≤ 0.1)

Frail patients were admitted to the hospital because of irAEs significantly more often than fit patients (29% vs 54%; P = .02) and showed a trend toward increased length of hospitalization (5 vs 8 days; P = .06) and more frequent use of immunosuppressants or ICI discontinuation for irAEs (36% vs 58%; P = .06).

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