Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis.

Transl Psychiatry · 2022 · PMC9325730 · PMID 35882855

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an observed trendno p-value reported

Our first key finding was an observed trend towards heightened heterogeneity in individuals at CHR-P in a cluster of frontal, temporal and hippocampal regions compared with HC.

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a numerical trendno p-value reported

Regional SV There was a numerical trend towards higher heterogeneity in CHR-P compared to HC individuals in the left hippocampus (VR = 1.07, 95% CI: 1.01–1.13), notwithstanding FDR corrections (Fig. 3 ).

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failed to reach statistical significanceno p-value reported

To summarise, we observed a trend towards regional heterogeneity (as measured by the variability ratio) in a cluster of frontal, temporal and hippocampal regions that failed to reach statistical significance after correction for multiple comparisons.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.