Nonrandom sister chromatid segregation mediates rDNA copy number maintenance in <i>Drosophila</i>.

Note that the asymmetry score in the rDNA amount (GSC/GB) did not reach statistical significance between control and indra GD9748 under magnifying conditions ( Fig. 4E , top); however, plotting the ratio of stronger over weaker rDNA signal ( Fig. 4E , bottom), it became clear that the magnifying condition induced copy number asymmetry in control ( bb z9 /Ybb − ), whereas this asymmetry itself was abrogated following depletion of indra ( bb z9 /Ybb − , nos-gal4>UAS-indra GD9748 , and UAS-Dcr-2 ) ( Fig. 4E , bottom).

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