Increased Serum NSE and S100B Indicate Neuronal and Glial Alterations in Subjects Under 71 Years With Mild Neurocognitive Disorder/Mild Cognitive Impairment.

Front Cell Neurosci · 2022 · PMC9329528 · PMID 35910248

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showed a trendp = 0.09so close (0.05 < p ≤ 0.1)

The regression model for NSE [R 2 = 0.03, F (3, 234) = 2.65, p = 0.05] revealed a significant effect for group, i.e., increased values in mild NCD compared to healthy controls (β = 0.29, t (230) = −1.75, p = 0.04), whereas age (β = −0.0006, t (230) = −0.39, p = 0.69) was not significant and interaction showed a trend (β = 0.004, t (230) = 1.67, p = 0.09).

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