Istradefylline for OFF Episodes in Parkinson's Disease: A US Perspective of Common Clinical Scenarios.

Degener Neurol Neuromuscul Dis · 2022 · PMC9329678 · PMID 35910426

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did not reach statistical significanceno p-value reported

73 However, a subanalysis of another 52-week open-label study found that the benefits of istradefylline on fatigue (MDS-UPDRS Part 1, item 13) did not reach statistical significance. 74 Clinical Scenario 7: Elderly PD with OFF Episodes Concerned with the Neuropsychiatric Side Effects of Other Adjunctive Medication Typical case description: 80-year-old man with PD diagnosed 6 years ago.

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