Epidemiological and clinical aspects of hepatitis B virus infection in Italy over the last 50 years.

World J Gastroenterol · 2022 · PMC9331523 · PMID 36051347

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a clear trendno p-value reported

Figure 1 shows a clear trend towards an overtime reduction of the total number of cases in Italy, and moderate changes in cases distribution, increased in northern and central regions and decreased in southern and island areas[ 26 , 27 ].

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