Relevance of Pathogenetic Mechanisms to Clinical Effectiveness of B-Cell-Depleting Monoclonal Antibodies in Multiple Sclerosis.

J Clin Med · 2022 · PMC9332715 · PMID 35893382

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showed a trendno p-value reported

Coupled with the observation that PRL showed a trend towards expansion, while rim negative lesions showed a trend towards shrinkage, it was suggested that PRL could be a biomarker of SELs and compartmentalised inflammation [ 64 ].

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