Notably, an association between IL13Rα1 overexpression and biochemical recurrence was also observed in the GSE70769 dataset ( Figure 1B ; N = 497, P = 0.06), although this association did not reach statistical significance ( Figure 1B ).
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IL13Rα1 prevents a castration resistant phenotype of prostate cancer by targeting hexokinase 2 for ubiquitin-mediated degradation.
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