SOD2 activity, measured after inactivation of SOD1 by Cu-chelation, only showed a statistical trend towards higher activity in the DMOG + SI group (Fig. 3J ).
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Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction.
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4J , Supplementary File 1 ) and FTH showed a trend towards higher levels in DMOG + SI co-treatment (Fig. 4K , Supplementary File 1 ).