Oxysterol derivatives Oxy186 and Oxy210 inhibit WNT signaling in non-small cell lung cancer.

Cell Biosci · 2022 · PMC9338492 · PMID 35908024

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a decreasing trendno p-value reported

RT-qPCR analysis also showed a decreasing trend of GLI2 and PTCH2 expression in Oxy210-treated samples; however, no statistically significance could be assigned comparing to those of the control group (Fig. 6 B).

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did not reach statistical significanceno p-value reported

Similar to the levels of GLI2 and PTCH2 expression in Oxy210-treated samples, these three genes were also downregulated in the Oxy210-treated xenografts, but the difference comparing to those of the control group did not reach statistical significance (Additional file 1 : Fig.

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