Research on a Weighted Gene Co-expression Network Analysis method for mining pathogenic genes in thyroid cancer.

In this study, WGCNA was used to screen the modules of mRNA and lncRNA that showed a significant trend in the development of TC, including one brown module of mRNA and one yellow module of lncRNA.

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Usage of databases By WGCNA, we obtained the mRNA module and lncRNA module that exhibit a highly significant correlation. miRcode [ 28 ] was used to predict the targeted miRNA by lncRNA in the lncRNA module with significant correlations.Targetscan [ 29 ] and miRDB [ 30 ] were used to predict mRNAs associated with miRNA.

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